Articles and information about side effects of steroids by shrenksonlinepharma
By: Code Platter
Anavar. Unlike most oral steroids, which are Class II steroids
giving most of their anabolic effect by means other than the
androgen receptor (AR), it seems that oxandrolone probably does
have good binding to the AR, and is therefore a Class I steroid,
while having little other effect. By itself it is considered to be
a weak anabolic.
Partly this is due to its apparent lack of non-AR-mediated
activity. This can be corrected of course by stacking with a Class
II steroid such as Dianabol, Anadrol, 4-AD, or nor-4-AD: the latter
two steroids require high blood levels which are not obtained by
oral use of the powders.
The other part of the reason for this is that bodybuilders make
unfortunate and unreasonable comparisons when judging anabolic
steroids. If say 8 tablets per day does little, then the drug is
pronounced useless or weak by the user. But that is only 20 mg/day,
or 140 mg/week. Does 140 mg/week testosterone give much results?
No. Few anabolic steroids give dramatic results at that dose. Per
milligram the potency is reasonable, but each individual tablet is
weak because the dosage is small.
Because of its high price, very few bodybuilders have taken large
doses of oxandrolone. There is a single case in the medical
literature (Forbes et al.) where it is reported that a competitive
athlete self-administered 150 mg oxandrolone per day with
remarkable gains. This is of uncertain credibility because unless
urinalysis was done to verify that no other steroids were taken,
there is no way to be certain that the athlete did not actually
take more drugs than he reported. In any case, at current prices,
only the quite wealthy could afford such a dose. I personally have
tried 150 mg/day and considered it somewhat effective, but not
dramatically so, and not a preferred regimen.
Oxandrolone does not aromatize or convert to DHT, and has a longer
half life than Dianabol - 8 hours vs. 4 hours. Thus, a moderate
dose taken in the morning is largely out of the system by night,
yet supplies reasonable levels of androgen during the day and early
evening.
Oxandrolone shares the liver toxicity problems common to
17-alkylated steroids. At one time it was thought that it did not,
but both clinical and practical experience with Oxandrin has shown
that at doses of 40 mg/day and higher, liver toxicity is indeed an
issue with prolonged use.
Primobolan, I believe, should be considered a superior compound,
offering the same activity at (usually) a lower price and without
the alkylated-toxicity issue.
Trivial name Oxandrolone
Systematic name 17-Hydroxy-17-methyl-2-
oxa-5-androstan-3-one
CAS number 53-39-4
ATC code A14AA08
Merck Index Number 6990
Chemical formula C19H30O3
Molecular weight 306.4442 g/mol
Bioavailability 97%
Metabolism Hepatic
Elimination half-life 8 hours
Excretion Urinary: 90%
Fecal: 6%
Pregnancy category X
Routes of administration Oral
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Tags: anabolic
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